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All links accessed November 4 2022

  1. Foundation for Liver Research. Liver Disease in the UK. https://www.liver-research.org.uk/liver-foundation/liver-disease-uk.html
  2. British Liver Trust. Statistics. https://britishlivertrust.org.uk/about-us/media-centre/statistics/
  3. Office for Health Improvement and Disparities (OHID). Guidance: ‘Liver disease: applying All Our Health’. Updated May 6 2022. https://www.gov.uk/government/publications/liver-disease-applying-all-our-health/liver-disease-applying-all-our-health
  4. OHID. Official Statistics. ‘Liver disease profiles, January 2022 update’. Updated 1 March 2022. https://www.gov.uk/government/statistics/liver-disease-profiles-january-2022-update/liver-disease-profiles-january-2022-update
  5. British Liver Trust. Risks and causes. https://britishlivertrust.org.uk/information-and-support/risks-and-causes/
  6. British Liver Trust. Executive summary: statistics at a glance - The alarming impact of liver disease in the UK. June 2019. https://britishlivertrust.org.uk/wp-content/uploads/The-alarming-impact-of-liver-disease-Executive-Summary-FINAL-June-2019.pdf
  7. NHS Health A to Z. Liver disease. Last reviewed October 2020. https://www.nhs.uk/conditions/liver-disease/
  8. NHS Inform. Liver disease. Last updated February 2020. https://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/liver-disease
  9. Cancer Research UK. Liver cancer statistics. https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/liver-cancer
  10. British Liver Trust. About the liver. https://britishlivertrust.org.uk/information-and-support/liver-health-2/abouttheliver/
  11. Johns Hopkins Medicine. Health Conditions and Diseases. ‘Liver: Anatomy and Functions’. https://www.hopkinsmedicine.org/health/conditions-and-diseases/liver-anatomy-and-functions
  12. The Hepatitis C Trust. Inside the liver. http://hepctrust.org.uk/information/liver/inside-liver
  13. AT Nguyen-Lefebvre and A Horuzsko. ‘Kupffer Cell Metabolism and Function’. J Enzymol Metab. 2015; 1(1): 101. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771376/
  14. AJ Highton et al. ‘The role of natural killer cells in liver inflammation’. Seminars in Immunopathology. July 7 2021. 43: 519–533. https://link.springer.com/article/10.1007/s00281-021-00877-6
  15. C Yin et al. ‘Hepatic stellate cells in liver development, regeneration, and cancer’. The Journal of Clinical Investigation. May 1 2013. 123;5: 1902-10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635734/
  16. British Liver Trust. Cirrhosis of the liver. https://britishlivertrust.org.uk/information-and-support/living-with-a-liver-condition/liver-conditions/cirrhosis/
  17. AE Barry et al. ‘Hepatic Stellate Cells and Hepatocarcinogenesis’. Front. Cell Dev. Biol. August 5 2020. https://www.frontiersin.org/articles/10.3389/fcell.2020.00709/full
  18. Johns Hopkins Medicine. Health Conditions and Diseases. ‘Portal Hypertension Symptoms’. https://www.hopkinsmedicine.org/health/conditions-and-diseases/portal-hypertension
  19. Cleveland Clinic. Hepatic Encephalopathy. Page last reviewed April 2020. https://my.clevelandclinic.org/health/diseases/21220-hepatic-encephalopathy
  20. NA Osna et al. ‘Alcoholic Liver Disease: Pathogenesis and Current Management’. Alcohol research: current reviews. 2017. 38;2: 147-161. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513682/
  21. R Loomba et al. ‘Mechanisms and disease consequences of nonalcoholic fatty liver disease’. Cell. May 13 2021. 184;10: 2537-2564. https://www.sciencedirect.com/science/article/pii/S0092867421004943
  22. NICE. BNF. Prescribing in hepatic impairment. https://bnf.nice.org.uk/medicines-guidance/prescribing-in-hepatic-impairment/
  23. L Hennessy and J Tweed. ‘Prescribing for patients with liver disease’. Hospital Pharmacy Europe. February 9 2012. https://hospitalpharmacyeurope.com/news/editors-pick/prescribing-for-patients-with-liver-disease/
  24. ES Björnsson. ‘Hepatotoxicity by Drugs: The Most Common Implicated Agents’. Int J Mol Sci. February 6 2016. 17;2:224. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783956/
  25. N Chalasani et al. ‘The Diagnosis and Management of Nonalcoholic Fatty Liver Disease: Practice Guidance From the American Association for the Study of Liver Diseases’. Hepatology. December 19 2017. 67;1:328-357. https://aasldpubs.onlinelibrary.wiley.com/doi/epdf/10.1002/hep.29367
  26. RA Weersink et al. ‘Prevalence of Drug Prescriptions and Potential Safety in Patients with Cirrhosis: A Retrospective Real-World Study’. Drug Safety. April 2019. 42;4: 539-546. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450857/
  27. NICE Guideline NG50. ‘Cirrhosis in over 16s: assessment and management’. July 6 2016. https://www.nice.org.uk/guidance/ng50/
  28. British Liver Trust. ‘Liver disease is the most common cause of ascites’. January 22 2020. https://britishlivertrust.org.uk/what-is-ascites/
  29. NICE BNF Treatment summaries. ‘Hepatitis’. https://bnf.nice.org.uk/treatment-summaries/hepatitis/

 

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