In Europe, the latest annual figures (for 2019) indicate that more than half of E. coli isolates and more than a third of K. pneumoniae isolates were resistant to at least one antimicrobial group, and there is often combined resistance to several antimicrobial groups.3 
The European Centre for Disease Prevention and Control (ECDPC) reported particular concern over increases in the percentage of vancomycin-resistant isolates of Enterococcus faecium in the EU/EEA, up from 10.5 per cent in 2015 to 18.3 per cent in 2019. Carbapenem resistance was common in Pseudomonas aeruginosa and Acinetobacter species, and at higher percentages than in K. pneumoniae.  
Interestingly, MRSA levels have been declining, although levels are still considered high in several countries and combined resistance to another antimicrobial group was common. There have also been improvements in Streptococcus pneumoniae resistance to penicillins and macrolide antibiotics.