Mycoplasma genitalium (referred to as Mgen or MG) is a sexually transmitted bacterial infection which is often asymptomatic but can cause urogenital symptoms.24 
Diagnoses almost tripled in 2019 to 5,300 cases, following increased testing availability. It is detected in up to a quarter of men with non-gonococcal urethritis and one in eight women with PID and has been shown to damage fallopian tube ciliary cells.14,24 
Lacking a cell wall, M genitalium will not take up Gram staining which makes it hard to detect, and it can also evade the immune system. It is of particular concern as it rapidly develops antimicrobial resistance, especially against macrolide antibiotics, meaning treatment should be in a genitourinary specialist setting.24 
A consequence of its antimicrobial resistance, possibly through overuse of single dose azithromycin, is that specialists are recommending that “azithromycin 1g as a single dose should no longer be used for any sexually transmitted infection.”24