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With the vaccination programme in full swing, we look at the principles behind the new SARS-CoV-2 vaccines...
After completing this module, you should be more aware of:
- the nature and structure of SARS-CoV-2
- why spike, or S proteins, on the virus capsule are the focus of vaccine research
- other potential targets for inactivating or eliminating the virus
- the range of vaccine platforms and their modes of action
- how RNA and DNA vaccines work, and specifically the new mRNA vaccines
- the seven vaccines the UK is expecting to use against Covid-19
- differences between the BioNTech/Pfizer and the Moderna mRNA vaccines
- the basis of the University of Oxford/AstraZeneca vaccine
- JCVI advice about vaccine selection and dosing regimes
- The priority groups for vaccination
- Contraindications, use in pregnancy, and adverse effects including anaphylaxis