Flu vaccine in pill form breakthrough
Researchersâ€¯fromâ€¯Cardiff University haveâ€¯created the worldâ€™s first synthetic, non-biologic vaccine.â€¯â€¯
Theâ€¯non-biologicâ€¯influenza vaccine, which can beâ€¯delivered orally, could herald a revolution inâ€¯vaccine delivery.â€¯
Stable at room temperature, the newâ€¯type of vaccine, which could be given in pill form, does notâ€¯require refrigerationâ€¯â€“ a process that can account for most of the cost of delivery of many current vaccines.
Professor Andrew Sewell, from Cardiff Universityâ€™s School of Medicine, who led the study, said: â€œThere are many benefits to oral vaccines. Not only would they be great news for people who have a fear of needles but they can alsoâ€¯be much easier to store and transport, making them far more suitable for use in remote locations where current vaccine delivery systemsâ€¯can be problematic.â€â€¯
The Research was funded by Wellcome and BBSRC and is published in the Journal of Clinical Investigation.
Divya Shah, from Wellcomeâ€™s Infection and Immunobiology team, said: â€œThis is a very exciting first proof of concept study that could provide a potential route to make vaccines that are thermostable and be administered orally. This could reduce the cost and increase accessibility across the globe, however much more research is needed to translate the findings into real-world vaccines.â€
Researchers point out thatÂ is likely to take several years before a non-biologic vaccine could be tested in humans.
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