Previously co-dydramol (dihydrocodeine/paracetamol) was available only in the ratio 1:50 (co-dydramol 10/500 mg). However, two new products are now available with a higher strength of dihydrocodeine (co-dydramol 20/500 mg and 30/500 mg tablets). It is therefore important that co-dydramol products are correctly prescribed and dispensed by strength to minimise dispensing errors and the risk of accidental opioid overdose. If in doubt, contact the prescriber.